|
KMID : 0604520210470030219
|
|
Journal of the Society of Cosmetic Scientists of Korea
2021 Volume.47 No. 3 p.219 ~ p.226
|
|
|
Studies on Antioxidant, Anti-inflammation and Moisturizing Activities of Gastrodia elata Flower Extract
|
|
Lee Hong-Gu
Kim Gil-Nam
Park Dong-Jun
Lee So-Young
Jin Mu-Hyun
|
|
|
Abstract
|
|
|
|
Gastrodia elata has a very low pollination rate in natural state, and even in artificial cultivation, there are very few individuals that bloom due to the degeneration, so little studies have been conducted. This study confirmed that the potential as a cosmetic ingredient by evaluating the antioxidant activity through the evaluation of DPPH radical scavenging activity, anti-inflammatory activity through the inhibitory effect on nitric oxide production, and the moisturizing activity through the effect on promoting hyaluronic acid production by artificially flowering G. elata flower. It was also confirmed that the appearance rate and flowering rate of G. elata harvested in spring were high, and the content of gastrodin was 0.36%. The IC50 value of G. elata flower extract was 0.045% and it was confirmed that G. elata flower extract had higher radical scavenging activity than G. elata root extract. The NO production inhibitory activity against the flower extract showed a significant inhibitory effect from 1% to 83.2%. Hyaluronic acid production promotion efficacy was not confirmed in the G. elata root extract, but the production rate increased with concentration dependence in the flower extract, and it was the highest at 46.9% when 0.02% treatment was performed. Based on the above research results, it is judged that G. elata flower extract has high potential for use as an antioxidant, anti-inflammatory, and skin moisturizing cosmetic ingredient.
|
|
|
KEYWORD
|
|
|
gastrodia elata flower, antioxidant, anti-inflammatory, hyaluronic acid, gastrodin
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|